EXPLORING APPROACHES FOR INVESTIGATING PHYTOCHEMISTRY: METHODS AND TECHNIQUES
Main Article Content
Rohit Saxena
The extraction, isolation, and analysis of bioactive compounds from plants are fundamental in the study of medicinal plants. This review explores various techniques and methods used for the extraction, isolation, and analysis of bioactive compounds from plant materials. Traditional methods such as maceration, percolation, and Soxhlet extraction are commonly used, but novel techniques have emerged to enhance efficiency and selectivity. Microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), pressurized liquid extraction (PLE), supercritical fluid extraction (SFE), and enzyme-assisted extraction are modern approaches that offer improved yields and efficiency. After extraction, bioactive compounds need to be characterized and analyzed. Chromatographic techniques, such as high-performance liquid chromatography (HPLC) and gas chromatography (GC), are commonly employed for separation and quantification. Spectroscopic techniques, including nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), provide valuable structural information. The continuous development of extraction and analytical techniques contributes to the discovery and utilization of bioactive compounds from plants in various applications. Future research can explore metabolomics, high-throughput screening, chemoinformatics, network pharmacology, multivariate data analysis, and computational modeling to enhance phytochemical investigations. The proposed methods and techniques complement traditional approaches, expanding our understanding of plant chemistry and its potential applications.
Smith, R. M. (2003). Techniques for extraction of bioactive compounds from plant materials: A review. Trends in Analytical Chemistry, 22(6), 361-371.
Mathesius, U. (2017). Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts. Plants, 6(4), 42.
Altemimi, A., Lakhssassi, N., Baharlouei, A., Watson, D. G., & Lightfoot, D. A. (2017). Phytochemicals: extraction, isolation, and identification of bioactive compounds from plant extracts. Plants, 6(4), 42.
Majors, R. E. (1999). Extraction, Isolation and Characterization of Bioactive Compounds from Plants' Extracts. African Journal of Traditional, Complementary, and Alternative Medicines, 8(1), 1-10.
Roche, M. (2022). A Comprehensive Review on the Techniques for Extraction of Bioactive Compounds from Medicinal Cannabis. Molecules, 27(3), 604.
Liu, Q., et al. (2021). Selective extraction of bioactive compounds from plants using recent extraction techniques: A review. Journal of Cleaner Production, 290, 125638.
Acharya, K., Ghosh, S., & Biswas, R. (2018). Extraction Techniques for Plant-Based Bio-active Compounds. FABAP Journal of Pharmaceutical Sciences, 43, 17-24.
Abbott, A. P., et al. (2003). Novel solvent properties of choline chloride/urea mixtures. ChemComm, 1, 70-71.
Abbott, A. P., et al. (2004). Deep eutectic solvents formed between choline chloride and carboxylic acids: versatile alternatives to ionic liquids. Journal of the American Chemical Society, 126(29), 9142-9147.
Paiva, M. D., et al. (2022). Sustainable extraction bioactive compounds procedures in medicinal plants based on the principles of green analytical chemistry: A review. Journal of Molecular Liquids, 344, 118874.
Gharaati Jahromi, S. (2019). Extraction Techniques of Phenolic Compounds from Plants. IntechOpen. doi: 10.5772/intechopen.84705
Halouzka, R., Zeljković, S.Ć., Klejdus, B. et al. (2020). Analytical methods in strigolactone research. Plant Methods 16, 76 https://doi.org/10.1186/s13007-020-00616-2
Lu Zhang et al. (2021). Advances in Metagenomics and Its Application in Environmental Microorganisms. Frontiers in Microbiology, 12, https://doi.org/10.3389/fmicb.2021.766364
Brown, A. (2016). Evaluating sources: A guide. The Writing Center at the University of North Carolina at Chapel Hill. Retrieved from https://writingcenter.unc.edu/tips-and-tools/evaluating-sources/
Johnson, P. (2020). Sampling Methods. The SAGE Encyclopedia of Research Methods. doi: 10.4135/9781483381428.n544
Jones, R., Rathi, D., Gupta, S., & Strachan, N. (2018). Validity and reliability in social science research. In SAGE Research Methods Foundations. doi: 10.4135/9781526421036826420
Lee, D. (2015). Data Cleaning: Problems and Current Approaches. ISRN Software Engineering, 1-11. doi: 10.1155/2015/912470
Smith, J. K. (2017). Accuracy. In Encyclopedia of Social Theory. doi: 10.4135/9781412952622.n14
Smith, N., & Johnson, K. (2018). Research ethics and informed consent. In SAGE Research Methods Foundations. doi: 10.4135/9781526421036826706
Thompson, B. (2019). Reliability. In Encyclopedia of Research Design. doi: 10.4135/9781412961280.n348
Nur Ilham, R. ., Arliansyah, A., Juanda, R., Multazam, M. ., & Saifanur, A. . (2021). RELATHIONSIP BETWEEN MONEY VELOCITY AND INFLATION TO INCREASING STOCK INVESTMENT RETURN: EFFECTIVE STRATEGIC BY JAKARTA AUTOMATED TRADING SYSTEM NEXT GENERATION (JATS-NG) PLATFORM. International Journal of Economic, Business, Accounting, Agriculture Management and Sharia Administration (IJEBAS), 1(1), 87–92. https://doi.org/10.54443/ijebas.v1i1.27
Yusuf Iis, E., Wahyuddin, W., Thoyib, A., Nur Ilham, R., & Sinta, I. (2022). THE EFFECT OF CAREER DEVELOPMENT AND WORK ENVIRONMENT ON EMPLOYEE PERFORMANCE WITH WORK MOTIVATION AS INTERVENING VARIABLE AT THE OFFICE OF AGRICULTURE AND LIVESTOCK IN ACEH. International Journal of Economic, Business, Accounting, Agriculture Management and Sharia Administration (IJEBAS), 2(2), 227–236. https://doi.org/10.54443/ijebas.v2i2.191
Geovani, I. ., Nurkhotijah, S. ., Kurniawan, H. ., Milanie, F., & Nur Ilham, R. . (2021). JURIDICAL ANALYSIS OF VICTIMS OF THE ECONOMIC EXPLOITATION OF CHILDREN UNDER THE AGE TO REALIZE LEGAL PROTECTION FROM HUMAN RIGHTS ASPECTS: RESEARCH STUDY AT THE OFFICE OF SOCIAL AND COMMUNITY EMPOWERMENT IN BATAM CITY. International Journal of Educational Review, Law And Social Sciences (IJERLAS), 1(1), 45–52. https://doi.org/10.54443/ijerlas.v1i1.10
Bustani, B., Khaddafi, M. ., & Nur Ilham, R. (2022). REGIONAL FINANCIAL MANAGEMENT SYSTEM OF REGENCY/CITY REGIONAL ORIGINAL INCOME IN ACEH PROVINCE PERIOD YEAR 2016-2020. International Journal of Educational Review, Law And Social Sciences (IJERLAS), 2(3), 459–468. https://doi.org/10.54443/ijerlas.v2i3.277
Nur Ilham, R., Heikal, M. ., Khaddafi, M. ., F, F., Ichsan, I., F, F., Abbas, D. ., Fauzul Hakim Hasibuan, A. ., Munandar, M., & Chalirafi, C. (2021). Survey of Leading Commodities Of Aceh Province As Academic Effort To Join And Build The Country. IRPITAGE JOURNAL, 1(1), 13–18. https://doi.org/10.54443/irpitage.v1i1.19
Nur ilham, R., Likdanawati, L., Hamdiah, H., Adnan, A., & Sinta, I. . (2022). COMMUNITY SERVICE ACTIVITIES “SOCIALIZATION AVOID STUDY INVESTMENT” TO THE STUDENT BOND OF SERDANG BEDAGAI. IRPITAGE JOURNAL, 2(2), 61–64. https://doi.org/10.54443/irpitage.v2i2.312
Falahuddin, F., Fuadi, . F., Munandar, M., Juanda, R. ., & Nur Ilham, R. . (2022). INCREASING BUSINESS SUPPORTING CAPACITY IN MSMES BUSINESS GROUP TEMPE BUNGONG NANGGROE KERUPUK IN SYAMTALIRA ARON DISTRICT, UTARA ACEH REGENCY. IRPITAGE JOURNAL, 2(2), 65–68. https://doi.org/10.54443/irpitage.v2i2.313
Majied Sumatrani Saragih, M. ., Hikmah Saragih, U. ., & Nur Ilham, R. . (2021). RELATIONSHIP BETWEEN MOTIVATION AND EXTRINSIC MOTIVATION TO ICREASING ENTREPRENEURSHIP IMPLEMENTATION FROM SPP AL-FALAH GROUP AT BLOK 10 VILLAGE DOLOK MASIHUL. MORFAI JOURNAL, 1(1), 1–12. https://doi.org/10.54443/morfai.v1i1.11
Sandi, H. ., Afni Yunita, N. ., Heikal, M. ., Nur Ilham, R. ., & Sinta, I. . (2021). RELATIONSHIP BETWEEN BUDGET PARTICIPATION, JOB CHARACTERISTICS, EMOTIONAL INTELLIGENCE AND WORK MOTIVATION AS MEDIATOR VARIABLES TO STRENGTHENING USER POWER PERFORMANCE: AN EMPERICAL EVIDENCE FROM INDONESIA GOVERNMENT. MORFAI JOURNAL, 1(1), 36–48. https://doi.org/10.54443/morfai.v1i1.14
Sinurat, M. ., Heikal, M. ., Simanjuntak, A. ., Siahaan, R. ., & Nur Ilham, R. . (2021). PRODUCT QUALITY ON CONSUMER PURCHASE INTEREST WITH CUSTOMER SATISFACTION AS A VARIABLE INTERVENING IN BLACK ONLINE STORE HIGH CLICK MARKET: Case Study on Customers of the Tebing Tinggi Black Market Online Store. MORFAI JOURNAL, 1(1), 13–21. https://doi.org/10.54443/morfai.v1i1.12
Ilham, Rico Nur. et all (2019). Investigation of the Bitcoin Effects on the Country Revenues via Virtual Tax Transactions for Purchasing Management. International Journal of Suplly Management.Volume 8 No.6 December 2019.
Ilham, Rico Nur. et all (2019).. Comparative of the Supply Chain and Block Chains to Increase the Country Revenues via Virtual Tax Transactions and Replacing Future of Money. International Journal of Suplly Management.Volume 8 No.5 August 2019.
Lasta Irawan, A. ., Briggs, D. ., Muhammad Azami, T. ., & Nurfaliza, N. (2021). THE EFFECT OF POSITION PROMOTION ON EMPLOYEE SATISFACTION WITH COMPENSATION AS INTERVENING VARIABLES: (Case Study on Harvesting Employees of PT. Karya Hevea Indonesia). International Journal of Social Science, Educational, Economics, Agriculture Research, and Technology (IJSET), 1(1), 11–20. https://doi.org/10.54443/ijset.v1i1.2
Rahmaniar, R., Subhan, S., Saharuddin, S., Nur Ilham, R. ., & Anwar, K. . (2022). THE INFLUENCE OF ENTREPRENEURSHIP ASPECTS ON THE SUCCESS OF THE CHIPS INDUSTRY IN MATANG GLUMPANG DUA AND PANTON PUMP. International Journal of Social Science, Educational, Economics, Agriculture Research, and Technology (IJSET), 1(7), 337–348. https://doi.org/10.54443/ijset.v1i7.36
likdanawati, likdanawati, Yanita, Y., Hamdiah, H., Nur Ilham, R., & Sinta, I. (2022). EFFECT OF ORGANIZATIONAL COMMITMENT, WORK MOTIVATION AND LEADERSHIP STYLE ON EMPLOYEE PERFORMANCE OF PT. ACEH DISTRIBUS INDO RAYA. International Journal of Social Science, Educational, Economics, Agriculture Research, and Technology (IJSET), 1(8), 377–382. https://doi.org/10.54443/ijset.v1i8.41
Nur Ilham, R., Arliansyah, A., Juanda, R. ., Sinta, I. ., Multazam, M. ., & Syahputri, L. . (2022). APPLICATION OF GOOD CORPORATE GOVERNANCE PRINCIPLES IN IMPROVING BENEFITS OF STATE-OWNED ENTERPRISES (An Emperical Evidence from Indonesian Stock Exchange at Moment of Covid-19). International Journal of Economic, Business, Accounting, Agriculture Management and Sharia Administration (IJEBAS), 2(5), 761–772. https://doi.org/10.54443/ijebas.v2i5.410
Rico Nur Ilham, Irada Sinta, & Mangasi Sinurat. (2022). THE EFFECT OF TECHNICAL ANALYSIS ON CRYPTOCURRENCY INVESTMENT RETURNS WITH THE 5 (FIVE) HIGHEST MARKET CAPITALIZATIONS IN INDONESIA. Jurnal Ekonomi, 11(02), 1022–1035. Retrieved from http://ejournal.seaninstitute.or.id/index.php/Ekonomi/article/view/481
Nur ilham, R., Likdanawati, L., Hamdiah, H., Adnan, A., & Sinta, I. . (2022). COMMUNITY SERVICE ACTIVITIES “SOCIALIZATION AVOID STUDY INVESTMENT” TO THE STUDENT BOND OF SERDANG BEDAGAI. IRPITAGE JOURNAL, 2(2), 61–64. https://doi.org/10.54443/irpitage.v2i2.312
Wayan Mertha, I. ., & Mahfud, M. (2022). HISTORY LEARNING BASED ON WORDWALL APPLICATIONS TO IMPROVE STUDENT LEARNING RESULTS CLASS X IPS IN MA AS’ADIYAH KETAPANG. International Journal of Educational Review, Law And Social Sciences (IJERLAS), 2(5), 507–612. https://doi.org/10.54443/ijerlas.v2i5.369
Mahfud, M., Yudiana, I. K., & Sariyanto, S. (2022). HISTORY OF BANYUWANGI KALIKLATAK PLANTATION AND ITS IMPACT ON SURROUNDING COMMUNITIES. International Journal of Educational Review, Law And Social Sciences (IJERLAS), 3(1), 91–104. https://doi.org/10.54443/ijerlas.v3i1.492
Mahfud et all (2021). PEMANFAATAN TRADISI RESIK LAWON SUKU USING SEBAGAI SUMBER BELAJAR SEJARAH LOKAL PADA SMA DI BANYUWANGI. Media Bina Ilmiah Vol.16 No.3 Oktober 2021. http://ejurnal.binawakya.or.id/index.php/MBI/article/view/1294/pdf
Sinta, I., Nur Ilham, R. ., Authar ND, M. ., M. Subhan, & Amru Usman. (2022). UTILIZATION OF DIGITAL MEDIA IN MARKETING GAYO ARABICA COFFEE. IRPITAGE JOURNAL, 2(3), 103–108. https://doi.org/10.54443/irpitage.v2i3.467
Nur Ilham, R., Arliansyah, A., Juanda, R. ., Sinta, I. ., Multazam, M. ., & Syahputri, L. . (2022). APPLICATION OF GOOD CORPORATE GOVERNANCE PRINCIPLES IN IMPROVING BENEFITS OF STATE-OWNED ENTERPRISES (An Emperical Evidence from Indonesian Stock Exchange at Moment of Covid-19). International Journal of Economic, Business, Accounting, Agriculture Management and Sharia Administration (IJEBAS), 2(5), 761–772. https://doi.org/10.54443/ijebas.v2i5.410
Mahfud et all (2020). Developing a Problem-Based Learning Model through E-Learning for Historical Subjects to Enhance Students Learning Outcomes at SMA Negeri 1 Rogojampi. IOP Conf. Series: Earth and Environmental Science 485 (2020) 012014 doi:10.1088/1755-1315/485/1/012014
Bhat, R. M., & Rajeshwari, R. (2022). Social Status of Women in Early Kashmir. Journal homepage: www. ijrpr. com ISSN, 2582(7421), 26-31.
Bhat, R. M. (2022). An Analytical Study of the Kushan Rule in Kashmir. Journal of Psychology and Political Science (JPPS) ISSN 2799-1024, 2(04), 9-14.
Bhat, R. M. (2022). A Historical Study of Prostitution. Journal of Media, Culture and Communication (JMCC) ISSN: 2799-1245, 2(04), 1-6.
Bhat, R. M. (2022). Women Exploitation in the Contemporary India: Importance of Media to Impede it. Journal of Women Empowerment and Studies (JWES) ISSN: 2799-1253, 2(02), 27-30.
Bhat, R. M. (2022). Dr. BR Ambedkar’s Views on Religion and Conversion to Buddhism: An Analytical Study. Journal of Legal Subjects (JLS) ISSN, 25-31.
Bhat, R. M. (2022). Ghandian Phase: Mahila-Samitis and the Role of Women in the Indian National Movement. Journal of Women Empowerment and Studies (JWES) ISSN: 2799-1253, 2(01), 26-29.
Bhat, R. M. (2021). Reign of Utpala Dyansty with Special Reference to Avantiverman (855-883 AD): His Irrigation Works and Agricultural Development-A Historical Study. International Journal of Agriculture and Animal Production (IJAAP) ISSN 2799-0907, 1(02), 10-16.
Bhat, R. M. (2022). CULTURAL HERITAGE OF EARLY KASHMIR-A STUDY. International Journal of Educational Review, Law And Social Sciences (IJERLAS), 2(4), 571-576.
Bhat, R. M. (2019). Ghadar Movement: Har Dayal and His Ideological Formulations. Think India Journal, 22(14), 2353-2363.
Bhat, R. M. (2022). Legacy of Buddhism in Kashmir. Journal of Psychology and Political Science (JPPS) ISSN 2799-1024, 2(03), 23-30.
Bhat, R. M. (2018). Shawl Industry in Kashmir from 1846-1907 with Special Reference to the Dogra Rule. In Source: Proceedings of the South Indian History Congress (Vol. 38, pp. 554-557).
Bhat, R. M. (2023). DR. BHIM RAO AMBEDKAR’S ADVOCACY OF WOMEN RIGHTS. MORFAI JOURNAL, 2(4), 730-736.
Bhat, R. M. (2023). THE GHADAR MOVEMENT: IGNITING THE FLAME OF FREEDOM IN INDIA. International Journal of Educational Review, Law And Social Sciences (IJERLAS), 3(4), 1123-1131.
Bhat, R. M., Rajan, P., & Gamage, L. (2023). Redressing Historical Bias: Exploring the Path to an Accurate Representation of the Past. Journal of Social Science, 4(3), 698-705.
Bhat, R. M. (2022). Queen Yasovati: A Descriptive Study on her Leadership in the Kingdom of Kashmir. Journal of Psychology and Political Science (JPPS) ISSN 2799-1024, 2(05), 11-17.
Bhat, R. M., & Rajeshwari, R. (2022, December). DIASPORIC CULTURE AND INTERNATIONAL RELATIONS-A HISTORICAL STUDY. In International Conference on Health Science, Green Economics, Educational Review and Technology (Vol. 4, pp. 41-46).
Bhat, R. M. (2022). Historical Review of Indian Constitution. TRADITIONAL JOURNAL OF LAW AND SOCIAL SCIENCES, 1(02), 100-110.
Bhat, R. M., Silllalee, A., & Kandasamy, L. S. (2023). Concepts and Contexts: The Interplay of Philosophy and History in Understanding Human Society. East Asian Journal of Multidisciplinary Research, 2(6), 2581-2590.
Bhat, R. M. (2022). Legacy of Buddhism in Kashmir. Journal of Psychology and Political Science (JPPS) ISSN 2799-1024, 2(03), 23-30.
