PHYTOCHEMICAL SCREENING AND GC-MS ANALYSIS OF ETHANOLIC EXTRACT OF Chromolaena odorata LEAVES

Aditya Candra; Tahara Dilla Santi; Ika Waraztuty; Syarifah Nora Andrianty; Andri; Said Aandy Saida

Authors

Aditya Candra Universitas Abulyatama
Tahara Dilla Santi Universitas Muhammadiyah Aceh
Ika Waraztuty Universitas Syiah Kuala
Syarifah Nora Andrianty Universitas Abulyatama
Andri Universitas Abulyatama
Said Aandy Saida Universitas Abulyatama

Keywords:

Chromolaena odorata leaves, extract, screening phytochemical, GC-MS, pharmacological activity

Abstract

Chromolaena odorata leaves are empirically known to act as anti-inflammatory and other pharmacological effects. In this study, ethanol extracts from Chromolaena odorata leaves were analyzed using phytochemical screening and gas chromatography-mass spectrometry (GC-MS) to identify phytochemical constituents. Phytochemical tests showed the presence of flavonoids, alkaloids, tannins, saponins, and phenolics. GC-MS analysis of ethanol extracts from Chromolaena odorata leaves detected the presence of seven phytochemical compounds, namely Ethyl (E)-4-(2-phenylethylamino)but-2-enoate; 2h-pyran 2-(7-heptadecynyloxy) tetrahydro; 3,7,11-Trimethyldodeca-2,6,10-trienyl acetate; Bicyclo(3.1.1)heptane, 2,6,6-trimethyl-,(1alpha,2beta,5alpha)-11,13-Dimethyl-12-tetradecen-1-yl acetate; (2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecen-1-ol, and 9,12,15-Octadecatrienoic acid. This study identified several constituents that are biologically active compounds through GC-MS. These phytocompounds have potential as herbal medicines due to pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, antibacterial, and anticancer.

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